Clomipramine Withdrawal and Tapering Help

Anafranil (Clomipramine) is a tricyclic antidepressant (TCA) that was developed in the early 1960s by the Swiss pharmaceutical company Geigy, known today as Novartis. Anafranil is a derivative of Imipramine, an earlier generation tricyclic.

Tricyclic antidepressants, including Clomipramine, were among the first drugs used for depression. Clomipramine has significant side effects and can be especially dangerous in overdose. Tricylics seems to block the reabsorption of Serotonin and Epinephrine back into nerve cells after the neurotransmitters are released into the synapse (a structure that permits the nerve cell to pass an electrical signal). This forces both Serotonin and Epinephrine levels higher in the brain, but prevents these critical neurotransmitters from recirculating throughout the body. Both Serotonin and Epinephrine are essential for gastrointestinal health, blood platelets, the central nervous system, cardiovascular region, respiratory system, liver, and adrenal glands.  This may explain why the side effects and withdrawal symptoms of Clomipramine are so widespread.

Anafranil (Clomipramine) is approved by the FDA but only for the treatment of Obsessive Compulsive Disorder OCD but is used off-label for depression, panic disorder, body dysmorphic, premature ejaculation, chronic pain, enuresis (bedwetting) and trichotillomania (hair pulling).  Clomipramine is distributed in breast milk and nursing is not recommended while taking Clomipramine due to the congenital defect risk to the newborn.

Clomipramine withdrawal symptoms can occur during gradual and particularly when abruptly stopping. It is strongly recommended to taper slowly yet too many find the withdrawal symptoms interfere with every aspect of life and require assistance to calm the nervous system throughout the process.

Our team of experts incorporates slow titration schedules combined with all-natural nutraceuticals to ease Clomipramine Withdrawal Symptoms.  Our nonprofit has assisted people in 73 countries and we are also here to help you too.

If you need help to taper Clomipramine, please send our nonprofit a confidential inquiry, telephone tollfree 866.605.2333 or get started on our program today.

How Point of Return can Help You

The Point of Return Program is an in-home tapering program that allows you to gradually lessen the amount of Clomipramine while also implementing the use of all-natural, calming nutraceuticals to ease symptoms.  Clomipramine is dangerous to abruptly or rapidly stop and our program is a proven, viable, low-cost option to continue living your life while tapering.

We are prescription drug experts that specialize in Antidepressant withdrawals.

How Our Clomipramine Withdrawal Program Works:


  • Our non-profit team guides you every step of the way through your Clomipramine taper.

  • The Point of Return program includes nutraceuticals to help minimize symptoms.

  • We eliminate possible interaction items so your Clomipramine withdrawal is more comfortable.

  • Instead of adding in other medications in an attempt to reduce withdrawal, we take an all-natural, non-drugging approach to Clomipramine dependency.

  • Begin our program and start the process of escaping Clomipramine addiction.


Included in our Clomipramine Withdrawal Program




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*Because prescription medications can cause severe withdrawal reactions, do not stop taking any medication without first consulting your physician. The decision to taper any medication should be discussed with your doctor and done with their consent and support. More...









Clomipramine Withdrawal Symptoms May Include:

Dry Mouth, Constipation, Bladder problems; particular improper elimination of urine, Sexual problems, Blurred Vision, Dizziness, Drowsiness, Increased heart rate, Coma, Stroke, Arrhythmias, Hyoptension, Seizures, Hallucinations, Abnormal involuntary movements, Excitement, Anxiety, Restlessness, Insomnia, Nightmares, Weakness, Fatigue, Tremors, Edema of the face and tongue, Bone marrow depression

Clomipramine Side Effects May Include:

    abdominal cramps, agitation, anxiety, black tongue, blurred vision, breast development in males, breast enlargement, confusion, constipation, delusions, diarrhea, dilation of pupils, disorientation, dizziness, drowsiness, dry mouth, excessive or spontaneous flow of milk, excessive urination at night, fatigue, fever, fluid retention, flushing, frequent urination, hair loss, hallucinations, headache, heart attack, high or low blood pressure, high or low blood sugar, hives, impotence, inability to sleep, inability to urinate, increased or decreased sex drive, inflammation of the mouth, intestinal blockage, itching, loss of appetite, loss of coordination, nausea, nightmares, numbness, panic, perspiration, pins and needles in the arms and legs, rapid, fluttery, or irregular heartbeat, rash, reddish or purplish spots on skin, restlessness, ringing in the ears, seizures, sensitivity to light, stomach upset, strange taste, stroke, swelling of the testicles, swollen glands, tingling, tremors, vision problems, vomiting, weakness, weight gain or loss, yellow eyes and skin

    Other Names for Clomipramine include: Anafranil

    Click here for more information on antidepressants...

    *Because prescription medications can cause severe withdrawal reactions, do not stop taking any medication without first consulting your physician. The decision to taper any medication should be discussed with your doctor and done with their consent and support. More...


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People We've Helped

I am now sleeping GREAT and the nutrients has helped me with that!! It really, truly works!

"First of all, I want to say there is hope for all of you who are going through a trial you feel will never end! I give glory to God for directing my path to Point of Return!"
-Debbie H., (California) Temazepam, Paxil, Neurontin

I am doing well and very excited to be antidepressant free

"I found the program very helpful and will be forever grateful. Thank you from the bottom of my heart."
-Dennis N., (Washington) Lexapro

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