Imovane Withdrawal and Tapering Help

Imovane (Zopiclone, Zimovane) is a nonbenzodiazepine hypnotic agent used in the treatment of insomnia and is recommended for short-term use only (7 consecutive days). It was introduced on the world market in 1988 but is not available in the United States, although its active molecular formula, Eszopiclone, is sold under the name Lunesta. Imovane (Zopiclone, Zimovane) is a controlled substance in the United States, Japan, Brazil, and some European countries. Sepracor Pharmaceutical separated the active compound of Zopiclone and patented it as Lunesta.

Imovane (Zopiclone, Zimovane) is known as a Z-drug because all the drugs in this classification begin with the letter Z. Z drugs were initially thought to be less addictive but time has shown a high risk of dependence and withdrawal symptoms. Initially Zopiclone was marketed as a safer alternative to benzodiazepines but a meta analysis (quantitative statistical analysis) found there are few clear and consisten differences between Zopiclone (Imovane) and benzodiazepines in terms of sleep onset, sleep duration, number of awakenings, quality of sleep, adverse events, tolerance, rebound insomnia and daytime alertness. More common reactions to Zopiclone show a reduction in total time spent in REM sleep. Imovane (Zopiclone, Zimovane) has shown it may have a greater addictive potential than Benzodiazepines and has been described as a "benzodiazepine in disguise". Tolerance to the effects of Zopiclone can develop after a few weeks and abrupt withdrawal (particularly after prolonged use) can cause seizures and delirium.

Zopiclone was first developed by Sepracor and introduced in 1986 by Rhone-Poulenc S.A., now part of Sanofi-Aventis who is the main manufacturer. On April 4, 2005 the United States Drug Enforcement Agency listed Zopiclone under Schedule IV, due to the evidence that the drug has addictive properties similar to benzodiazepines.

Imovane (Zopiclone, Zimovane) is not recommended during pregnancy as it is secreted in human milk and its concentrations may reach 50% of the plasma levels. Zopiclone is not recommended to nursing mothers.

Imovane (Zopiclone, Zimovane) works on GABA (Gamma-Aminobutyric Acid) that slows the brain activity to induce sleep. Continued use of Imovane (Zopiclone, Zimovane) down-regulates GABA and higher doses of Imovane are required. This state of tolerance causes sleep to erode further and daytime anxiety increases.

Imovane is cross-tolerant to Benzodiazepines and Alcohol, meaning that once tolerance to Imovane develops, the patient will also have tolerance to any Benzodiazepine and Alcohol. This places recovering alcoholics or benzodiazepine dependent individuals at a higher risk for dependency to Imovane.

Due to the high dependence risk and effect on the GABA receptor, a gradual taper is recommended. Yet many find that even with a slow titration the withdrawal symptoms from Imovane are interrupting every aspect of life. This is why our nonprofit incorporates slow titration schedules with calming, all-natural nutraceuticals to help ease Imovane Withdrawal symptoms, making the taper more comfortable.

We have helped people in 73 countries over the last 11 years and we can also help you.

If you'd like our assistance to taper Imovane please send our nonprofit a confidential inquiry, telephone tollfree 866.605.2333 or get started on our program today.

How Point of Return can Help You

The Point of Return Program is an in-home tapering program that allows you to gradually lessen the amount of Imovane while also implementing the use of all-natural, calming nutraceuticals to help ease symptoms.  Imovane is dangerous to abruptly or rapidly stop and our program is a proven, viable, low-cost option to continue living your life while tapering.

We are prescription drug experts that specialize in Sleeping Pill withdrawals.

How Our Imovane Withdrawal Program Works:

  • The nonprofit team at Point of Return expertly guides you throughout the Imovane Tapering process.
  • Our Enhanced Nutraceuticals are provided to help minimize Imovane Withdrawal.
  • We identify Interaction items to help make Imovane withdrawal more comfortable
  • Our physician recommended schedules allow your doctor to taper you off Imovane correctly.


Included in Your Imovane Withdrawal Program


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Disclaimer: *Because prescription medications can cause severe withdrawal reactions, do not stop taking any medication without first consulting your physician. The decision to taper any medication should be discussed with your doctor and must be done with their consent and support. More...

Imovane Withdrawal Symptoms May Include:

abdominal pains, aching, agoraphobia, anxiety, blurred vision, body vibrations, changes in perception, diarrhea, distended abdomen, feeling of unreality, flu-like symptoms, flatulence, food cravings, hair loss, heart palpitations, heavy limbs, increased allergies, increased sense of smell, insomnia, lethargy, loss of balance, metallic taste, muscle spasms, nightmares, panic attacks, paranoia, persistent & unpleasant memories, severe headaches, shaking, short term memory loss, sore mouth and tongue, sound & light sensitivity, speech difficulties, sweating, suicidal thoughts, tinnitus, unusually sensitive, fear

Imovane Abrupt Discontinuation Symptoms May Include:

    abdominal & muscle cramps, vomiting, sweating, shakiness, & rarely, seizures may occur & finally rebound insomnia

    Imovane Side Effects May Include:

    drowsiness, dizziness, lightheadedness, difficulty with coordination, memory loss or amnesia, tolerance, dependence, changes in behavior and thinking; such as more outgoing or aggressive behavior than normal, confusion, strange behavior, agitation, hallucinations, worsening of depression, suicidal thoughts

    Other Names for Imovane: (Zopiclone, Zimovane)

    Click here for more information on benzodiazepines...

    Withdrawal Brochure:

    Download our brochure to learn more about our tapering programs. MORE...


    Disclaimer: *Because prescription medications can cause severe withdrawal reactions, do not stop taking any medication without first consulting your physician. The decision to taper any medication should be discussed with your doctor and must be done with their consent and support. More...

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People We've Helped

I am now sleeping GREAT and the nutrients has helped me with that!! It really, truly works!

"Now I am pill free and sleeping great! I know, with out a doubt, that had I not found Point of Return, I would still be struggling and desperate."-Rita M., (Canada) Eszopiclone (Zopiclone, Lunesta)

I am once again feeling creative and purposeful in my life

"If you feel trapped by pharmaceuticals like SSRI's and Benzodiazepines please know that there is hope. I am now free of the grip of Ativan and Klonopin. The Point of Return products and staff are the key to reclaiming your life! You can do this. I know because I've been there".
-Paul M., (California) Ativan, Klonopin

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