Savella Withdrawal Help

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Savella Withdrawal

Savella Withdrawal Symptoms may include but not limited to:

Savella taperingaggression, anxiety, balance issues , blurred vision , brain zaps, concentration impairment, constipation, crying spells, depersonalization, diarrhea, dizziness. electric shock sensations, fatigue, flatulence, flu-like symptoms, hallucinations, hostility, highly emotional, indigestion, irritability, impaired speech, insomnia, jumpy nerves, lack of coordination, lethargy, migraine headaches / increased headaches, nausea, nervousness, over-reacting to situations, paranoia, repetitive thoughts or songs, sensory & sleep disturbances, severe internal restlessness (akathisia), stomach cramps, tremors, tinnitus (ear ringing or buzzing), tingling sensations, troubling thoughts, visual hallucinations / illusions, vivid dreams, speech or visual changes, worsened depression

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(Milnacipran, Dalcipran, Ixel)

Savella is an antidepressant in a group of drugs called Selective Serotonin and Norepinephrine Reuptake Inhibitors (SSNRIs).

Norepinephrine is both a hormone and a neurotransmitter, and as a hormone is secreted by the adrenal gland. It is almost identical in structure to epinephrine and works in conjunction with epinephrine and adrenaline to give the body the sudden energy it needs in times of stress. This is known as the “fight or flight” response. The sympathetic nervous system functions in response to short-term stress and both Norepinephrine and Epinephrine increase the heart rate as well as blood pressure. Other actions of Norepinephrine include the conversion of glycogen to glucose in the liver, the conversion of fats to fatty acids in the fat tissue, and relaxation of the bronchial muscle to open the air passages to the lungs. All of these actions represent the flight or fight response.

As a neurotransmitter, Norepinephrine passes nerve impulses from one nerve cell to the next and is important for attention, emotions, sleeping, dreaming and learning. Mild elevations in our Norepinephrine levels create heightened arousal, a state produced by stimulants. This increased sense of arousal is what links many substances to their potential for addiction. Some individuals using SNRIs develop a state of emotional elation (hypomania) and are cautioned to notify their treating physician/psychiatrist, as it is a sign of Norepinephrine levels increasing too high. But this condition is often mistaken as an easing of depression and goes unreported or addressed.

Moderately high levels of Norepinephrine create a sense of arousal that is uncomfortable and includes intensified worrying, anxiety, increased startle reflex, jumpiness, fear of crowds and tight places, impaired concentration, and restless sleep.  All these symptoms are also side effects of SNRIs as are rapid fatigue, muscle tension/cramps, irritability and a sense of being on edge.  SNRIs can cause blood pressure to increase, so it is recommended to carefully monitor while on the medication.

Serotonin contributes to various body functions, such as regulating body temperature, sleep, mood, appetite and pain. 95% of our Serotonin is located in the gut region where it regulates intestinal movements, with the vast majority of Serotonin is in the enteroendocrine (endocrine cells pertaining to hormones) of the gastrointestinal tract. If irritants (pesticides, preservatives, etc) are present, the stomach region releases more Serotonin to make the gut move faster, i.e., to cause diarrhea so the area is emptied of the noxious substance.  Antidepressants can cause both diarrhea and constipation, depending on the action of Serotonin in the gut region. Many antidepressants have shown to lower Serotonin levels below the baseline after chronic use, despite the initial increases. Therefore the benefit may decrease after long-term treatment.

People We've Helped

  • My sincere wish and hope is that the public becomes more aware of the danger of the drugs and also as many people as possible can get out of the ever endless hell of drug addiction safely and continue to feel great. - Mayu T., California (ZOLOFT, LORAZEPAM) more...
  • I would like to thank everyone at the POR office for helping me through this horrible time of my life, you were always there when I had a question or needed support. The program is the real deal and it works. I just wished I would have found Point of Return two years sooner! Dan C., Canada (PAXIL) more...
  • I really appreciate the gift of being able to be off the SSRI's because of the negative side effects they had. Thank you!!! Michel B.L., South Carolina (EFFEXOR) more...

Savella Side Effects


Symptoms may include but not limited to:

Abnormal dreams, Anxiety or nervousness, Body weakness, Chills, Cough, Difficulty sleeping, Dizziness, Drowsiness, fatigue or weakness, Dry mouth, Extreme elation or feeling of happiness that may alternate with a depressed or sad mood, Engaging in dangerous or unusual activities, Hallucinations, Headache, Heart Palpitations, High blood pressure (hypertension), Hostility or aggressiveness, Increased sweating, Loss of appetite or weight loss, Nausea, vomiting, indigestion, diarrhea or constipation, Restlessness or inability to sit still, Sexual problem, including decreased libido, Shakiness (tremor), Suicidal thoughts or behavior, Vision changes, Yawning


*While great care has been taken in organizing and presenting the material throughout this website, please note that it is provided for informational purposes only and should not be taken as Medical Advice. More...