Zoloft Withdrawal and Tapering Help

Zoloft's history dates back to the early 1970s when a scientist named Reinhard Sarges was working on a set of psychoactive compounds called tametraline for Pfizer Pharmaceutical. The initial development brought strange and unwanted side effects in animal tests but in 1977 two other scientists combined tematraline with other compounds and found a Serotonin Reuptake Inhibitor that later became Zoloft (Sertraline).

In 1991 Sertraline was officially approved by the FDA and in 2002, Zoloft was approved for use in children and teenagers under the age of 18 (with OCD). In 2005 the FDA added a warning label about Zoloft advising of suicidal behavior, but in 2007 the warning was revised to include young adults up to the age of 24. By 2013 Zoloft was the most prescribed antidepressant and second most prescribed psychiatric medication (Alprazolam was first) on the United States market, with over 41 million prescriptions.

Zoloft (Sertraline) is an antidepressant in a group of drugs called Selective Serotonin Reuptake Inhibitors (SSRIs) that exerts the majority of its action on Serotonin, with minimal effects on Norepinephrine and Dopamine.

Compared to other SSRIs (Selective Serotonin Reuptake Inhibitors), Zoloft tends to have a higher rate of psychiatric side effects including anxiety, agitation, and insomnia.

Serotonin influences the cardiovascular, renal, immune and gastrointestinal systems due to its effect on the contraction of smooth muscles, and is essential to regulate body temperature, heart rate, blood pressure and the sympathetic nervous system. The alteration of Serotonin by Zoloft explains the high rate of gut and cardiovascular related side effects. Patients on Zoloft have much higher rates of sexual dysfunction versus other antidepressants due to Zoloft's effect on Serotonin, but lower rates of cognitive decline from its secondary effect on Dopamine. In pregnant women, higher rates of birth defects have been associated with Zoloft due to significant concentrations being present in fetal blood.

Because SSRI's influence numerous systems of the body and brain, stopping Zoloft abruptly can cause a discontinuation syndrome known as withdrawal. 60% of Zoloft patients were found to experience Zoloft withdrawal symptoms.

Our nonprofit utilizes a gradual dose reduction (tapering), combined with specific all-natural nutraceuticals to help ease the symptoms during the Zoloft withdrawal process.

Over the past 11 years we have assisted people in 73 countries and are here to help you too.

If you'd like our assistance to taper Zoloft please send our nonprofit a confidential inquiry, telephone tollfree 866.605.2333 or get started on our program today.

How Point of Return can Help You

The Point of Return Program is an in-home tapering program that allows you to gradually lessen the amount of Zoloft while also implementing the use of all-natural, calming nutraceuticals to ease symptoms.  Zoloft is dangerous to abruptly or rapidly stop and our program is a proven, viable, low-cost option to continue living your life while tapering.

We are prescription drug experts that specialize in Antidepressant withdrawals.

How Our Zoloft Withdrawal Program Works:

  • Expert non-profit team that guides you through the process.
  • Zoloft Withdrawals are minimized by our specialized nutraceuticals .
  • We eliminate interaction items that can increase symptoms .
  • You taper slowly under our guidance and with your doctor's support .
  • Our private discussion board is available 24/7 provides a focus on healing .
  • Don't let Zoloft Withdrawals interfere with your life. Begin our program now.

Included in Your Zoloft Withdrawal Program

zoloft withdrawal program

*nutraceuticals are used throughout the taper

Other Withdrawal Programs

Benzodiazepine Program
For Benzodiazepine Medications. More..
Sleeping PIll Program
For Sleeping Pill Medications. More..
Protracted Withdrawal
For those off Medications and feel poorly. More..



Content on this page requires a newer version of Adobe Flash Player.

Get Adobe Flash player

    Disclaimer: *Because prescription medications can cause severe withdrawal reactions, do not stop taking any medication without first consulting your physician. The decision to taper any medication should be discussed with your doctor and must be done with their consent and support. More...




Zoloft Withdrawal Symptoms May Include:

aggression, anxiety, balance issues , blurred vision, brain zaps, concentration impairment, constipation, crying spells, depersonalization, diarrhea, dizziness. electric shock sensations, fatigue, flatulence, flu-like symptoms, hallucinations, hostility, highly emotional, indigestion, irritability, impaired speech, insomnia, jumpy nerves, lack of coordination, lethargy, migraine headaches / increased headaches, nausea, nervousness, over-reacting to situations, paranoia, repetitive thoughts or songs, sensory & sleep disturbances, severe internal restlessness (akathisia), stomach cramps, tremors, tinnitus (ear ringing or buzzing), tingling sensations, troubling thoughts, visual hallucinations / illusions, vivid dreams, speech or visual changes, worsened depression

Zoloft Side Effects May Include:

    abdominal pain, agitation, anxiety, constipation, decreased sex drive, diarrhea or loose stools, difficulty with ejaculation, dizziness, dry mouth, fatigue, gas, headache, decreased appetite, increased sweating, indigestion, insomnia, nausea, nervousness, pain, rash, sleepiness, sore throat, tingling or pins and needles, tremor, vision problems, vomiting, Acne, allergic reaction, altered taste, back pain, blindness, breast development in males, breast pain or enlargement, breathing difficulties, bruise-like marks on the skin, cataracts, changeable emotions, chest pain, cold, clammy skin, conjunctivitis (pinkeye), coughing, difficulty breathing, difficulty swallowing, double vision, dry eyes, eye pain, fainting, feeling faint upon arising from a sitting or lying position, feeling of illness, female and male sexual problems, fever, fluid retention, flushing, frequent urination, hair loss, heart attack, hemorrhoids, hiccups, high blood pressure, high pressure within the eye (glaucoma), hearing problems, hot flushes, impotence, inability to stay seated, increased appetite, increased salivation, increased sex drive, inflamed nasal passages, inflammation of the penis, intolerance to light, irregular heartbeat, itching, joint pains, kidney failure, lack of coordination, lack of sensation, leg cramps, menstrual problems, low blood pressure, migraine, movement problems, muscle cramps or weakness, need to urinate during the night, nosebleed, pain upon urination, prolonged erection, purplish spots on the skin, racing heartbeat, rectal hemorrhage, respiratory infection/lung problems, ringing in the ears, rolling eyes, sensitivity to light, sinus inflammation, skin eruptions or inflammation, sleepwalking, sores on tongue, speech problems, stomach and intestinal inflammation, swelling of the face and throat, swollen wrists and ankles, thirst, throbbing heartbeat, twitching, vaginal inflammation, hemorrhage or discharge, yawning, Abnormal dreams or thoughts, aggressiveness, exaggerated feeling of well-being, depersonalization ("unreal" feeling), hallucinations, impaired concentration, memory loss, paranoia, rapid mood shifts, suicidal thoughts, teeth-grinding, worsened depression.In a few people, Zoloft may trigger the grandiose, inappropriate, out-of-control behavior called mania or the similar, but less dramatic, "hyper" state called hypomania

    Other names for Zoloft include (Sertraline, Lustral, Serlain)

    Click here for more information on antidepressants...

    Withdrawal Brochure:

    Download our brochure to learn more about our tapering programs. MORE...


    Disclaimer: *Because prescription medications can cause severe withdrawal reactions, do not stop taking any medication without first consulting your physician. The decision to taper any medication should be discussed with your doctor and must be done with their consent and support. More...

Let us help!




Please enter the words MAKE THIS INQUIRY into the field below. It helps us avoid spam.


*Your information will never be shared,
sold or made available to 3rd parties.


People We've Helped

Alesandra, her staff and the company are my angels!

"Today I am alive and I can hold my beautiful son in my arms because of POR's help and her compassion." -Mayu T., (California) Zoloft (Sertraline), Lorazepam

I am doing well and very excited to be antidepressant free

"I found the program very helpful and will be forever grateful. Thank you from the bottom of my heart."
-Dennis N., (Washington) Lexapro

Frequently Asked Questions: Answers to commonly asked questions. MORE...